1122-10-7, 3,4-Dibromo-1H-pyrrole-2,5-dione is a pyrrolines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
(Indolin-3-yl)ethanole 2a (1.700 g, 10.4 mmol) and Et(iPr)2N(3.5 mL, 20 mmol) were added to solution of 3,4-dibrommalemide 1 (2.540 g, 10 mmol) in dry DMF (5 mL). The reaction mixture was left to stir overnight at 50 C. The cooled to rt reaction mixture was diluted with EtOAc (100 mL), washed with water (200 mL), brine (50 mL), dried, and evaporated. The residue was chromatographed (33.3% EtOAc/petroleum ether) to give 4a as a red amorphous solid (2.642 g, 7.8 mmol, 80%); mp 137-139 C; Rf (50% EtOAc/petroleumether) 0.35; vmax 1767, 1715, 1624, 1591 cm-1; deltaH (400 MHz, DMSO-d6): 1.60-1.69 (2H, m), 1.89-1.97 (2H, m), 3.52-3.55 (2H, m),4.00-4.05 (1H, m), 4.37-4.42 (1H, m), 6.95 (1H, d, J 8.0 Hz), 6.99(1H, t, J 7.5 Hz), 7.16 (1H, t, J 7.6 Hz), 7.25 (1H, d, J 7.5 Hz), 11.02 (1H,s); deltaC (100 MHz, DMSO-d6): 36.5, 38.3, 58.7, 59.5, 91.0 (q), 115.8,122.8, 123.9, 126.3, 136.4 (q), 141.7 (q), 142.0 (q), 166.8 (C=O), 167.1(C=O); HRMS [MNa]+, found: 358.9987, [C14H13BrN2O3Na] requires 359.0007.
1122-10-7, As the paragraph descriping shows that 1122-10-7 is playing an increasingly important role.
Reference£º
Article; Simonov, Alexander Y.; Bykov, Evgeny E.; Lakatosh, Sergey A.; Luzikov, Yury N.; Korolev, Alexander M.; Reznikova, Marina I.; Preobrazhenskaya, Maria N.; Tetrahedron; vol. 70; 3; (2014); p. 625 – 630;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem