55750-48-6, Methyl 2,5-dioxo-2,5-dihydro-1H-pyrrole-1-carboxylate is a pyrrolines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,55750-48-6
0-(P-D-glucopyranos-1 -yl)decyl-maleimide (38) N-(methoxycarbonyl) maleimide(37) (0.014 g, 0.09 mmol) was added at RT to a stirring solution of (10-Aminodecyl) p-D-glucopyranoside(0.015 g, 0.04 mmol) in dioxane (0.75 ml_) and sat. NaHC03 (aq) (1.5 ml_). The reaction was stirred for 1 hr after which the reaction was quenched with EtOAc (10 ml_) and water (10 mL). The organic phase was separated out and the aq. phase extracted with EtOAc (3 x 10 mL). The organic layers were combined, dried, filtered and the solvent evaporated under vacuum. The residue was adsorbed onto silica and purified with column chromatography (CH2CI2: MeOH 9: 1 ). The title compound was obtained as a clear oil (0.01 1 g, 60 %) Rf = 0.15 (CH2CI2: MeOH 9:1 ) deltaEta (CD3OD, 300 MHz): 6.79 (2H, s, 374′), 4.24 (1 H, d, J = 7.5 Hz, H-1 “), 3.93-3.84 (2H, m, H-6″a/H-10a), 3.69-3.64 (1 H, m, H-6″b), 3.57-3.50 (1 H, dt, J = 6.6, 9.6 Hz, H-10b), 3.48 (2H, t, J = 6.9 Hz, H-1 ), 3.38-3.22 (3H, m, H-3’74’75”), 3.19-3.13 (1 H, m, H-2″), 1.64-1 .54 (4H, m, H-2/9), 1.42-1 .28 (12H, m, AlkCHz). 5C (CD3OD, 100 MHz): 172.6 (C-275′), 135.3 (C-374′), 104.4 (C-1 “), 78.2 (C-3″), 77.9 (C-2″), 75.1 (C-5″), 71 .7 (C-10), 70.9 (C-4″), 62.8 (C-6”), 38.5 (C-1 ), 30.8 (C-2), 30.5 (x3), 30.1 , 29.4, 27.7, 27.0 (CH2Alk)
The synthetic route of 55750-48-6 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; THE SOUTH AFRICAN NUCLEAR ENERGY CORPORATION LIMITED; UNIVERSITY OF CAPE TOWN; DRIVER, Cathryn Helena Stanford; ZEEVAART, Jan Rijn; PARKER, Mohamed Iqbal; HUNTER, Roger; (67 pag.)WO2016/46793; (2016); A2;,
Pyrroline – Wikipedia
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