The molecularity of an elementary reaction is the number of molecules that collide during that step in the mechanism. If there is only a single reactant molecule in an elementary reaction, that step is designated as unimolecular.69778-83-2, name is 4-Methoxy-1H-pyrrol-2(5H)-one. A new synthetic method of this compound is introduced below., 69778-83-2
The 4-chloro-3-methoxy-2-E-butenoic acid, methyl ester thus obtained (84.42 g) was stirred with 210 ml of 28% aqueous ammonia solution under a reflux condenser at 80 C. for 2 hours. The mixture was then cooled to room temperature and extracted with methylene chloride. The extract was dried over sodium sulfate, filtered and solvent removed from the filtrate under reduced pressure. The residue was triturated with diethyl ether, giving 40, 6 g of 4-methoxy-3-pyrrolin-2-one, m.p. 132 C.
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Reference£º
Patent; Researche Syntex France, S.A.; US4997846; (1991); A;,
Pyrroline – Wikipedia
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