Synthetic Route of 1081-17-0, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.1081-17-0, Name is 1-(4-Methoxyphenyl)-1H-pyrrole-2,5-dione, molecular formula is C11H9NO3. In a Article£¬once mentioned of 1081-17-0
Novel inhibitors of urease from Corydalis govaniana Wall.
A new compound govaniadine (1), along with three known tetrahydroprotoberberine-type alkaloids caseadine (2), caseamine (3), and protopine (4), were isolated from the plant Corydalis govaniana Wall. All alkaloids 1-4 exhibited a good urease enzyme inhibition with IC50 ¡À S.E.M. values of 20.2 ¡À 3.6, 38.9 ¡À 2.8, 66.7 ¡À 1.2, and 54.1 ¡À 1.2 muM, respectively, which are comparable to the standard inhibitor, acetohydroxamic acid (IC50 = 42.0 muM). None of these compounds showed inhibition against alpha-chymotrypsin. This is the first report of urease inhibiting tetrahydroprotoberberine-type alkaloids.
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Reference£º
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem