The important role of 1-(2-Hydroxyethyl)-1H-pyrrole-2,5-dione

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1585-90-6, Name is 1-(2-Hydroxyethyl)-1H-pyrrole-2,5-dione, belongs to pyrrolines compound, is a common compound. name: 1-(2-Hydroxyethyl)-1H-pyrrole-2,5-dioneIn an article, once mentioned the new application about 1585-90-6.

A thermally-cleavable linker for solid-phase synthesis

Oxabicyclo[2.2.1]norbornenes constitute a convenient and readily cleaved linker for solid-phase organic synthesis. A simple and inexpensive furfuryl-substituted resin has been shown to capture and release maleimide dienophiles under conditions compatible with intermediate synthetic steps. The synthesis of beta-amino, -thiophenoxy, and -hydrazino alcohols by epoxide ring opening, and maleimide-functionalized Leu-enkephalin by standard peptide coupling techniques, are described to illustrate the utility of the solid-phase synthesis methodology.

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Reference£º
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem