Chemistry, like all the natural sciences, Recommanded Product: 112275-50-0, begins with the direct observation of nature¡ª in this case, of matter.112275-50-0, Name is tert-Butyl 1,4-diazepane-1-carboxylate, SMILES is O=C(N1CCNCCC1)OC(C)(C)C, belongs to pyrrolines compound. In a document, author is KOEHN, FE, introduce the new discover.
ANALOGS OF THE MARINE IMMUNOSUPPRESSANT MICROCOLIN-A – PREPARATION AND BIOLOGICAL-ACTIVITY
A series of analogs of the immunosuppressive lipopeptide microcolin A has been prepared and evaluated for in vitro activity in the human and murine two-way mixed lymphocyte reaction. The compounds tested were obtained by semisynthetic modification and chemical degradation of the natural product. The relative potencies of these analogs suggest that the hydroxyproline and 5-methyl-3-pyrrolin-2-one portion of the molecule are important for immunosuppressive activity and that other structural elements may play an ancillary role. Methanolysis of microcolin A also led to a novel immunosuppressive lactone analog.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 112275-50-0. Recommanded Product: 112275-50-0.
Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem