In an article, author is Liu, Zhuqing, once mentioned the application of 1953-02-2, Formula: C5H9NO3S, Name is Tiopronin, molecular formula is C5H9NO3S, molecular weight is 163.1949, MDL number is MFCD00004861, category is pyrrolines. Now introduce a scientific discovery about this category.
Selective 1,4-Addition of Organolithiums to Maleate Monoesters with Application for a Short Efficient Route to Azaindanones
The ability of maleate half-ester salts to serve as electrophilic partners in 1,4-conjugate addition reactions with control of regioselectivity has previously been explored in only a limited context with soft nucleophiles. We have demonstrated that benzylic anions of picolines, as well as enolates of ketones, esters, and nitriles, react with lithium 4-( tert -butoxy)-4-oxobutenoate in a completely regioselective manner. This new method was applied to an expedient two-step process for preparing a key azaindanone intermediate for the clinical-candidate drug MK-8666.
If you are interested in 1953-02-2, you can contact me at any time and look forward to more communication. Formula: C5H9NO3S.
Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem