New discoveries in chemical research and development in 2021.In classical electrochemical theory, both the electron transfer rate and the adsorption of reactants at the electrode control the electrochemical reaction. In an article, author is Abou-Elmagd, Wael S. I., once mentioned the application of 13676-54-5, Name is Bismaleimide, molecular formula is C21H14N2O4, molecular weight is 358.3469, MDL number is MFCD00005507, category is pyrrolines. Now introduce a scientific discovery about this category, Recommanded Product: 13676-54-5.
Conversion of Some 2(3H)-Furanones into Pyrrolinotriazine and Oxazolopyrimidine Derivatives
2(3H)-Furanones 1 were utilized for the construction of pyrrolinotriazine and oxazolopyrimidine derivatives 4 and 9. Thus, 1 reacted with glycine in ethanol at 70 degrees C to give the acids 2, which were cyclized into the pyrrolin-5-one derivatives 3 by the action of HCl/AcOH. The later compounds 3 were also obtained by refluxing the furanones 1 with glycine in glacial AcOH for 10 h. The carboxy functionality in 3 was used for the construction of a triazinone ring by treatment with thionyl chloride followed by refluxing the acid chloride with hydrazine in ethanol. The conversion of the furanones 1 into the oxazolopyrimidine derivatives 9 involved the following steps: (i) ring opening of the lactone ring with hydrazine hydrate to give the acid hydrazides 5, (ii) conversion of the hydrazides 5 into the corresponding acyl azides 6 by action of NaNO2/AcOH, (iv) base-catalyzed decomposition of the azides in the presence of glycine, (v) ring closure of the urea derivatives 7 into the pyrimidine derivatives 8, and finally (vi) condensing 8 with benzaldehyde in the presence of NaOAc/AcOH mixture.
The prevalence of solvent effects in heterogeneous catalysis in condensed media has motivated developing quantitative kinetic, their interactions with reaction intermediates. Interested yet? Read on for other articles about 13676-54-5. Recommanded Product: 13676-54-5.
Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem