New research progress on 54-47-7 in 2021. Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. 54-47-7, Name is Pyridoxal phosphate, molecular formula is C8H10NO6P, belongs to pyrrolines compound, is a common compound. In a patnet, author is Snider, BB, once mentioned the new application about 54-47-7, HPLC of Formula: https://www.ambeed.com/products/54-47-7.html.
A novel biomimetic route to the 3-acyl-5-hydroxy-3-pyrrolin-2-one and 3-acyl-3,4-epoxy-5-hydroxypyrrolidin-2-one ring systems
Modified Moffat oxidation of alcohols 17, 22, and 25 afforded aldehydes that underwent intramolecular aldol reactions on treatment with a NaOH solution to yield 4-pyrrolin-2-ones 16, 23, and 26. Oxidation with DMDO at -40 degreesC provided 3-acyl-5-hydroxy-3-pyrrolin-2-ones 18, 24, and 27 with the ring system of oteromycin (3), UCS1025A (5), and related natural products. Further oxidation of 18 yielded 3-acyl-3,4-epoxy-5-hydroxy-pyrrolidin-2-one 19 with the ring system of fusarin C (1) and epolactaene (2). Dehydration of 18 afforded 20 with the talaroconvolutin A (4) ring system.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 54-47-7. HPLC of Formula: https://www.ambeed.com/products/54-47-7.html.
Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem