Chemical engineers work across a number of sectors, processes differ within each of these areas, but chemistry and chemical engineering roles are found throughout, and are directly involved in the process of chemical products and materials. 1953-02-2, Name is Tiopronin, molecular formula is , belongs to pyrrolines compound. In a document, author is Cores, Angel, Quality Control of Tiopronin.
Three-component access to 2-pyrrolin-5-ones and their use in target-oriented and diversity-oriented synthesis
The Hantzsch-type microwave-assisted, solvent-free sequential three-component reaction between primary amines, beta-dicarbonyl compounds and alpha-bromoesters in the presence of indium trichloride afforded 2-pyrrolin-5-ones, which are difficult to access by alternative methods. Ready access to these compounds allowed their use as synthetic building blocks in a target-oriented project aimed at the synthesis of a compound that had previously been postulated as a candidate for HIV integrase inhibition on the basis of computational studies. The versatility of 2-pyrrolin-5-ones was further verified by their use in a diversity-oriented synthesis context, leading to a library of highly functionalized bispiro compounds. The overall process leading to these compounds involved the generation of six bonds and two cycles over three steps, two of which are multicomponent, and the fully controlled generation of up to four stereocenters, including two quaternary ones.
Quality Control of Tiopronin, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 1953-02-2.
Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem