Moore, Richard E.; Blackman, Adrian J.; Cheuk, Chad E.; Mynderse, Jon S.; Matsumoto, Gayle K.; Clardy, Jon; Woodard, Ronald W.; Craig, J. Cymerman published the article 《Absolute stereochemistries of the aplysiatoxins and oscillatoxin A》. Keywords: absolute configuration aplysiatoxin oscillatoxin; NMR proton aplysiatoxin oscillatoxin; CD aplysiatoxin oscillatoxin; crystal structure aplysiatoxin.They researched the compound: (R)-4-Hydroxydihydrofuran-2(3H)-one( cas:58081-05-3 ).Synthetic Route of C4H6O3. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:58081-05-3) here.
CD and proton NMR spectral studies of the aplysiatoxins and derivatives, degradation products of the toxins, and an X-ray crystallog. anal. of 19,21-dibromoaplysiatoxin show that the absolute configurations of the ten asym. carbons are 3S,4R,7S,9S,10S,11R,12S,15S,29R,30R. The 31-nor compound, oscillatoxin A, has the same absolute stereochem. at C(3), C(4), C(7), C(9), C(10), C(11), C(12), C(15), and C(29).
There is still a lot of research devoted to this compound(SMILES：O=C1OC[C@H](O)C1)Synthetic Route of C4H6O3, and with the development of science, more effects of this compound(58081-05-3) can be discovered.
Reference:
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem