So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Larcheveque, Marc; Henrot, Serge researched the compound: (R)-4-Hydroxydihydrofuran-2(3H)-one( cas:58081-05-3 ).Name: (R)-4-Hydroxydihydrofuran-2(3H)-one.They published the article 《New chiral synthons. β,γ-Epoxy esters. Application to the synthesis of enantiomerically pure β-hydroxy esters》 about this compound( cas:58081-05-3 ) in Tetrahedron Letters. Keywords: hydroxy ester chiral; epoxy ester chiral synthon. We’ll tell you more about this compound (cas:58081-05-3).
The preparation of optically pure β,γ-epoxy esters I (R = H, Me) was achieved through the opening of 3-hydroxy butanolides II with trimethylsilyl iodide followed by cyclization with silver oxide. I react with organocuprates to afford β-hydroxy esters III (R1 = Me, Et, Bu, Me2C:CH, BuCH:CH) of high enantiomeric purity.
Here is just a brief introduction to this compound(58081-05-3)Name: (R)-4-Hydroxydihydrofuran-2(3H)-one, more information about the compound((R)-4-Hydroxydihydrofuran-2(3H)-one) is in the article, you can click the link below.
Reference:
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem