Hollingsworth, Rawle I. published the article 《Taming carbohydrate complexity: a facile, high-yield route to chiral 2,3-dihydroxybutanoic acids and 4-hydroxytetrahydrofuran-2-ones with very high optical purity from pentose sugars》. Keywords: synthon hydroxybutanoic acid hydroxytetrahydrofuranone lactone preparation; hydroxybutanoic acid hydroxytetrahydrofuranone lactone preparation pentose sugar.They researched the compound: (R)-4-Hydroxydihydrofuran-2(3H)-one( cas:58081-05-3 ).Quality Control of (R)-4-Hydroxydihydrofuran-2(3H)-one. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:58081-05-3) here.
(S)-3,4-Dihydroxybutanoic acid and its γ-lactone [(S)-4-hydroxytetrahydrofuran-2-one] are important four-carbon synthons obtainable from some substituted D-hexose sugars and from L-malic acid. Until now there has been no easy route to the R-isomers because of the rarity both of suitably substituted L-hexose sugars and D-malic acid. Here we describe a method for preparing both enantiomeric forms of the free acids and their corresponding γ-lactones from pentose sugars.
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Reference:
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem