The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: (R)-4-Hydroxydihydrofuran-2(3H)-one(SMILESS: O=C1OC[C@H](O)C1,cas:58081-05-3) is researched.Reference of 4-Methoxypiperidine. The article 《Absolute stereochemistries of the aplysiatoxins and oscillatoxin A》 in relation to this compound, is published in Journal of Organic Chemistry. Let’s take a look at the latest research on this compound (cas:58081-05-3).
CD and proton NMR spectral studies of the aplysiatoxins and derivatives, degradation products of the toxins, and an X-ray crystallog. anal. of 19,21-dibromoaplysiatoxin show that the absolute configurations of the ten asym. carbons are 3S,4R,7S,9S,10S,11R,12S,15S,29R,30R. The 31-nor compound, oscillatoxin A, has the same absolute stereochem. at C(3), C(4), C(7), C(9), C(10), C(11), C(12), C(15), and C(29).
In addition to the literature in the link below, there is a lot of literature about this compound((R)-4-Hydroxydihydrofuran-2(3H)-one)HPLC of Formula: 58081-05-3, illustrating the importance and wide applicability of this compound(58081-05-3).
Reference:
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem