The effect of the change of synthetic route on the product 58081-05-3

When you point to this article, it is believed that you are also very interested in this compound(58081-05-3)Category: pyrrolines and due to space limitations, I can only present the most important information.

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called A novel generation of optically active ethyl 4-chloro-3-hydroxybutyrate as a C4 chiral building unit using microbial dechlorination, published in 1996-11-08, which mentions a compound: 58081-05-3, mainly applied to microbial stereoselective dechlorination chlorohydroxybutyrate, Category: pyrrolines.

A novel procedure for the generation of optically active Et 4-chloro-3-hydroxybutyrate using bacterial cells was developed. Et (S)-4-chloro-3-hydroxybutyrate was prepared by Pseudomonas sp. OS-K-29, which stereoselectively assimilates 2,3-dichloro-1-propanol. The reaction was based on its kinetic dehalogenation for both enantiomers using the resting cells. The obtained 4-chloro-3-hydroxybutyrate had high enantiomeric excess of >98% with a yield of 33% at the microbial resolution step. Moreover, several C4 compounds having the 4-chloro-3-hydroxyl function were also resolved and gave good enantiomeric purities (>95% ee). Et (R)-4-chloro-3-hydroxybutyrate was also obtained with high enantiomeric purity (>98% ee) using the cells of Pseudomonas sp DS-K-NR818.

When you point to this article, it is believed that you are also very interested in this compound(58081-05-3)Category: pyrrolines and due to space limitations, I can only present the most important information.

Reference:
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem