Synthetic Route of 272786-64-8, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C¨CH bond functionalisation has revolutionised modern synthetic chemistry. 272786-64-8, Name is 2-((4-Fluorophenyl)sulfonyl)hexahydropyrrolo[1,2-a]pyrazin-6(2H)-one, SMILES is O=C1CCC2CN(S(=O)(C3=CC=C(F)C=C3)=O)CCN21, belongs to pyrrolines compound. In a article, author is Sha, Qiang, introduce new discover of the category.
Synthesis of 1H-Pyrrol-3(2H)-ones via Three-Component Reactions of 2,3-Diketo Esters, Amines, and Ketones
An efficient one-pot, three-component reaction of 2,3-diketo esters with amines and ketones has been developed for the synthesis of 1H-pyrrol-3(2H)-ones. By using trifluoroacetic acid (TFA) as the additive and acetonitrile (MeCN) as the solvent, this convenient method provides a library of 1H-pyrrol-3(2H)-ones in moderate to good yields. The simple protocol features readily available starting materials, a straightforward process, good functional group tolerance, and broad substrate scope.
Synthetic Route of 272786-64-8, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 272786-64-8.
Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem