Chemical Research Letters, May 2021. As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world., Name: Dimethylglyoxime, Introducing a new discovery about 95-45-4, Name is Dimethylglyoxime, molecular formula is C4H8N2O2, belongs to pyrrolines compound. In a document, author is Smith, AB.
A second-generation synthesis of scalemic 3,5,5-trisubstituted pyrrolin-4-ones: Incorporation of functionalized amino acid side-chains
To access mimics of peptidal beta-strands (1), scalemic 3,5,5-trisubstituted pyrrolin-4-ones bearing the tyrosine, serine, and lysine side-chains have been generated via cyclization of metalated imino esters and deprotection. The functionalized imino esters were prepared by asymmetric alkylation of a common oxazolidinone precursor (2) derived from L-prenylglycine. (C) 1997 Elsevier Science Ltd.
The potential utility of systematic synthetic strategy will be applicable to efficient generations of chemical libraries of compounds to find ‘hit’ molecules. In my other articles, you can also check out more blogs about 95-45-4. Name: Dimethylglyoxime.
Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem