The prevalence of solvent effects in heterogeneous catalysis in condensed media has motivated developing quantitative kinetic, spectroscopic, and theoretical assessments of solvent structures and their interactions with reaction intermediates. 1707-03-5, Name is Diphenylphosphinic acid, molecular formula is C12H11O2P, belongs to pyrrolines compound, is a common compound. In a patnet, author is Shanmugasundaram, Muthian, once mentioned the new application about 1707-03-5, Application of 1707-03-5.
Highly regioselective 1,3-dipolar cycloaddition of 3 ‘-O-propargyl guanosine with nitrile oxide: An efficient method for the synthesis of guanosine containing isoxazole moiety
The 1,3-dipolar cycloaddition reaction of 3 ‘-O-propargyl guanosine with various in-situ generated nitrile oxides in the presence of DMF as a solvent is described. It is noteworthy that the reaction is highly regioselective that affords biologically important guanosine containing isoxazole moiety in good yields with high purities. (C) 2020 Elsevier Ltd. All rights reserved.
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Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem