Chemical engineers ensure the efficiency and safety of chemical processes, adapt the chemical make-up of products to meet environmental or economic needs, and apply new technologies to improve existing processes. 13676-54-5, Name is Bismaleimide, molecular formula is C21H14N2O4, belongs to pyrrolines compound, is a common compound. In a patnet, author is Sha, Qiang, once mentioned the new application about 13676-54-5, Application of 13676-54-5.
Synthesis of 1H-Pyrrol-3(2H)-ones via Three-Component Reactions of 2,3-Diketo Esters, Amines, and Ketones
An efficient one-pot, three-component reaction of 2,3-diketo esters with amines and ketones has been developed for the synthesis of 1H-pyrrol-3(2H)-ones. By using trifluoroacetic acid (TFA) as the additive and acetonitrile (MeCN) as the solvent, this convenient method provides a library of 1H-pyrrol-3(2H)-ones in moderate to good yields. The simple protocol features readily available starting materials, a straightforward process, good functional group tolerance, and broad substrate scope.
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Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem