The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 2-Chloro-5-iodo-3-methylpyridine(SMILESS: CC1=CC(I)=CN=C1Cl,cas:59782-89-7) is researched.Quality Control of (R)-4-Hydroxydihydrofuran-2(3H)-one. The article 《An improved procedure for the oxidation of 2,5- and 5,6-dihalo-3-methylpyridines》 in relation to this compound, is published in Organic Preparations and Procedures International. Let’s take a look at the latest research on this compound (cas:59782-89-7).
Nicotinic acids I (R = Br, Cl, F; R1 = iodo, Br, Cl) were obtained from methylpyridines II and Bu4N+ MnO4-. Similarly prepared were acids III (R2 = Br, Cl). 5,6-Dibromo-3-methylpyridine in pyridine was oxidized by Bu4N+ MnO4- at 75-80° to give III (R2 = Br).
This literature about this compound(59782-89-7)SDS of cas: 59782-89-7has given us a lot of inspiration, and I hope that the research on this compound(2-Chloro-5-iodo-3-methylpyridine) can be further advanced. Maybe we can get more compounds in a similar way.
Reference:
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem