The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: (R)-4-Hydroxydihydrofuran-2(3H)-one(SMILESS: O=C1OC[C@H](O)C1,cas:58081-05-3) is researched.HPLC of Formula: 58081-05-3. The article 《Total Synthesis of (+)-Mycotrienol and (+)-Mycotrienin I》 in relation to this compound, is published in Journal of Organic Chemistry. Let’s take a look at the latest research on this compound (cas:58081-05-3).
A highly convergent asym. synthesis of the ansamycin antibiotics (+)-mycotrienin I (I) (R = cyclohexylcarbonyl-D-Ala) and (+)-mycotrienol (I) (R = H) (II) has been achieved through the synthesis and coupling of the C9-C16 subunit (III) and the aromatic subunit (IV). All four stereogenic centers were introduced using chiral allylsilane bond construction methodol. A key feature of the synthetic scheme includes the incorporation of the (E, E, E)-triene unit with simultaneous macrocyclization via a Stille-type coupling-macrocyclization.
As far as I know, this compound(58081-05-3)Category: pyrrolines can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.
Reference:
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem