The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: (R)-4-Hydroxydihydrofuran-2(3H)-one(SMILESS: O=C1OC[C@H](O)C1,cas:58081-05-3) is researched.Recommanded Product: 58081-05-3. The article 《A Concise Stereoselective Total Synthesis of Methoxyl Citreochlorols and Their Structural Revisions》 in relation to this compound, is published in European Journal of Organic Chemistry. Let’s take a look at the latest research on this compound (cas:58081-05-3).
A concise, stereoselective and protecting group free approaches for the total synthesis of (-)-(2S,4R)- and (+)-(2R,4S)-3′-methoxyl citreochlorols, e.g., I, and their stereoisomers are demonstrated. All four stereoisomers were synthesized to establish the absolute stereochem. of the reported structures and the structures were revised accordingly. The approach involves chelation controlled regioselective reduction of a diester, silyl iodide promoted ring-opening iodo esterification of lactones, highly chemo- and regioselective ring-opening of an epoxy ester, dichloromethylation of a carboxyl group, and syn- and anti-selective reduction of the resulted β-hydroxy ketone as key steps.
Although many compounds look similar to this compound(58081-05-3)Synthetic Route of C4H6O3, numerous studies have shown that this compound(SMILES:O=C1OC[C@H](O)C1), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem