With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.31970-04-4,Benzyl 2,5-dihydro-1H-pyrrole-1-carboxylate,as a common compound, the synthetic route is as follows.
To a solution of benzyl 2,5-dihydro-l H-pyrrole-l -carboxylate (2.00 g, 9.80 mmol) in CH2C12 (10 mL) was added slowly 3-chloroperbenzoic acid (3.00 g, 14.80 mmol) at 0 ¡ãC. The reaction mixture was stirred for 13 h at room temperature, then quenched with saturated sodium thiosulfate aqueous solution and extracted with EtOAc. The organic phase was dried over anhydrous Na2S04 and concentrated in vacuo. The residue was chromatographed with a silica gel column (eluting agent: 6: 1 (v/v) PE/EtOAc) to give the title compound as colorless oil (1.75 g, 81.02 percent)., 31970-04-4
As the paragraph descriping shows that 31970-04-4 is playing an increasingly important role.
Reference£º
Patent; SUNSHINE LAKE PHARMA CO., LTD.; ZHANG, Jiancun; ZHANG, Yingjun; ZHANG, Weihong; LIU, Bing; ZHANG, Jiquan; LIU, Jinlei; ZHANG, Lu; WO2013/71697; (2013); A1;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem