Category: 1122-10-7

A balanced equation for a chemical reaction indicates what is reacting and what is produced, but it reveals nothing about how the reaction actually takes place. The reaction mechanism is the process, or pathway, by which a reaction occurs.1122-10-7, name is 3,4-Dibromo-1H-pyrrole-2,5-dione. An updated downstream synthesis route of 1122-10-7 as follows., 1122-10-7

General procedure: To the solution of dibromomaleimide 1a orN-methyldibromomaleimide 1b (1 mmol) in THF (20 ml)was added solution of the thiophenol (2.2 mmol) and triethylamine(2.2 mmol) in one portion. The resulting solutionwas stirred at room temperature for 1 h, then evaporated invacuo and the residue was redissolved in ethyl acetate-water(20 + 20 ml) mixture. The organic layer was separated,washed with aq. NaHCO3, dried over anhydrous Na2SO4and evaporated. The residue was purified by flash chromatography(ethyl acetate: petroleum ether 3:1)., 1122-10-7

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Article; Panov, Alexey A.; Lavrenov, Sergey N.; Simonov, Alexander Y.; Mirchink, Elena P.; Isakova, Elena B.; Trenin, Alexey S.; Journal of Antibiotics; vol. 72; 2; (2019); p. 122 – 124;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem

1122-10-7, An elementary termolecular reaction involves the simultaneous collision of three atoms, molecules, or ions.1122-10-7, name is 3,4-Dibromo-1H-pyrrole-2,5-dione. Here is a downstream synthesis route of the compound 1122-10-7

General procedure: To a stirred solution of 2,3-dibromomaleimide23 (1.0 mmol) in CH2Cl2 (20ml) Et3N (2.0mmol) and thiol (2.1mmol) were added under argon atmosphere and stirred for 3 h at room temperature. The reaction mixture was evaporated,and the crude product was purified by flash chromatography to give the desired compound., 1122-10-7

This molecular description is the mechanism of the reaction; it describes how individual atoms, ions, or molecules interact to form particular products.If you are interested, you can also browse other articles of 3,4-Dibromo-1H-pyrrole-2,5-dione. We look forward to the emergence of more reaction modes in the future.

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Article; Csavas, Magdolna; Miskovics, Adrienn; Szcs, Zsolt; Rth, Erzsebet; Nagy, Zsolt L; Bereczki, Ilona; Herczeg, Mihaly; Batta, Gyula; Nemes-Nikodem, Eva; Ostorhazi, Eszter; Rozgonyi, Ferenc; Borbas, Aniko; Herczegh, Pal; Journal of Antibiotics; vol. 68; 9; (2015); p. 579 – 585;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem

1122-10-7, A balanced equation for a chemical reaction indicates what is reacting and what is produced, but it reveals nothing about how the reaction actually takes place. The reaction mechanism is the process, or pathway, by which a reaction occurs.1122-10-7, name is 3,4-Dibromo-1H-pyrrole-2,5-dione. An updated downstream synthesis route of 1122-10-7 as follows.

General procedure: To a solution of N-R-maleimide (10 mmol) in CCl4 (15 mL) was added dropwise a solution of Br2 (0.57 mL, 11 mmol) in CCl4 (10mL) at rt After the addition is completed, the reaction mixture was refluxed for 1 h and then cooled to room temperature. The solvent was evaporated in vacuo to give the crude trans-2,3-Dibromo-N-R-succinimide as pale-yellow solid. The crude succinimide was dissolved in THF (30 mL) and triethylamine (1.40 mL, 11 mmol) in THF (5 mL) was added dropwise at 0 oC.The resulting mixture was allowed to warm to room temperature and stirred for two h before concentrated in vacuo. The residue was dissolved in EtOAc and washed with H2O and brine. The organic layer was dried with anhydrous Na2SO4 and evaporated in vacuo to give bromo-N-R-maleimide (1)as pale-yellow solid with good yields., 1122-10-7

A chemical reaction often occurs in steps, although it may not always be obvious to an observer. Thank you very much for taking the time to read this article. If you are also interested in other aspects of 3,4-Dibromo-1H-pyrrole-2,5-dione, you can also browse my other articles.

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Article; Li, Xiangmin; Li, Hongxian; Yang, Wei; Zhuang, Jinchen; Li, Hao; Wang, Wei; Tetrahedron Letters; vol. 57; 24; (2016); p. 2660 – 2663;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem

1122-10-7, The molecularity of an elementary reaction is the number of molecules that collide during that step in the mechanism. If there is only a single reactant molecule in an elementary reaction, that step is designated as unimolecular.1122-10-7, name is 3,4-Dibromo-1H-pyrrole-2,5-dione. A new synthetic method of this compound is introduced below.

General procedure: Dibromomaleimide 1a, 2.0 g (7.84 mmol), was dissolved in 15 mL of anhydrous DMF, and 0.9 mL (9.51 mmol) of 4-fluoroaniline and 2 mL (11.5 mmol) of DIPEA were added. The mixture was stirred for 24 h at 50C and poured into a mixture of water and ethyl acetate. The organic layer was separated, washed with dilute aqueous HCl, and evaporated under reduced pressure, and the residue was purified by column chromatography using petroleum ether-ethyl acetate (5 : 1) as eluent.

This molecular description is the mechanism of the reaction; it describes how individual atoms, ions, or molecules interact to form particular products.If you are interested, you can also browse other articles of 3,4-Dibromo-1H-pyrrole-2,5-dione. We look forward to the emergence of more reaction modes in the future.

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Article; Panov; Simonov, A. Yu.; Korolev; Russian Journal of Organic Chemistry; vol. 55; 12; (2019); p. 1847 – 1852; Zh. Org. Khim.; vol. 55; 12; (2019); p. 1850 – 1856,7;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem

The molecularity of an elementary reaction is the number of molecules that collide during that step in the mechanism. If there is only a single reactant molecule in an elementary reaction, that step is designated as unimolecular.1122-10-7, name is 3,4-Dibromo-1H-pyrrole-2,5-dione. A new synthetic method of this compound is introduced below., 1122-10-7

To a solution of 3,4-dibromomaleimide (1.00g, 3.9mmol) and N-methylmorpholine (0.43ml_, 3.90mmol) in THF (50ml_), methylchloroformate (0.30ml_, 3.90mmol) was added and the mixture was stirred for 20minutes at room temperature. To this mixture, dichloromethane (DCM, 40ml_) was added and the organic phase was washed with water (3x100ml_), dried with MgS04. The solvent was removed in vacuo to yield the titled product as a purple powder. 1H NMR (CDCIs, 300MHz) d (ppm): 4.01 (3H, s, COCH3). 13C NMR(CDCI3, 75MHz) d (ppm): 131 .4(C=C), 54.8 (COCH3)., 1122-10-7

Thank you very much for taking the time to read this article. If you are also interested in other aspects of 1122-10-7, you can also browse my other articles.

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Patent; UNILEVER PLC; UNILEVER N.V.; CONOPCO, INC., D/B/A UNILEVER; KHOSHDEL, Ezat; BATES, Susan; HAND, Rachel, Alice; HADDLETON, David, Mark; KIRBY, Gavin, William; (20 pag.)WO2019/201787; (2019); A1;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem

An elementary termolecular reaction involves the simultaneous collision of three atoms, molecules, or ions.1122-10-7, name is 3,4-Dibromo-1H-pyrrole-2,5-dione. Here is a downstream synthesis route of the compound 1122-10-7. 1122-10-7

To a stirred solution of 2,3-dibromomaleimide (510 mg, 2.0 mmol) in CH2Cl2 (20 mL) Et3N(558 mL, 4.0 mmol) and n-hexyl-mercaptan (600 ml, 4.2 mmol) wereadded under an argon atmosphere and stirred for 3 h at roomtemperature. The reaction mixture was evaporated, and the crudeproduct was purified by flash chromatography (hexanes:ethyl acetate 9:1) to give compound 6a (526 mg, 80%) as a yellow powder.1H NMR (400 MHz, CDCl3): d 7.88 (s, 1H), 3.28 (t, J 7.4 Hz, 4H,2 x -SCH2), 1.70e1.59 (m, 4H, CH2), 1.47e1.37 (m, 4H), 1.35e1.24 (m,8H), 0.89 (t, J 6.7 Hz, 6H, 2x CH3). 13C NMR (101 MHz, CDCl3):d 166.6 (2C); 136.8 (CC); 31.9, 31.4, 30.6, 28.3 (8C, 8x CH2); 22.6(2C, 2 x CH2S); 14.1 (2C, 2x CH3). MS (ESI): m/z calculated forC16H27NO2S2 Na [M Na]: 352.138. Found: 352.201.

There are, however, a few established termolecular elementary reactions. The reaction of nitric oxide with oxygen appears to involve termolecular steps. you can also browse my other articles about 1122-10-7

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Article; Sz?cs, Zsolt; Kelemen, Viktor; Le Thai, Son; Csavas, Magdolna; R?th, Erzsebet; Batta, Gyula; Stevaert, Annelies; Vanderlinden, Evelien; Naesens, Lieve; Herczegh, Pal; Borbas, Aniko; European Journal of Medicinal Chemistry; vol. 157; (2018); p. 1017 – 1030;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem

An elementary termolecular reaction involves the simultaneous collision of three atoms, molecules, or ions.1122-10-7, name is 3,4-Dibromo-1H-pyrrole-2,5-dione. Here is a downstream synthesis route of the compound 1122-10-7. 1122-10-7

Example 12 Preparation of Di-dansyl-cystamine-maleimide A round bottomed flask was charged with di-dansyl cystamine (100 mg, 0.16 mmol), TCEP (46 mg, 1 eq) and MeOH (10 ml). The reaction mixture was stirred at ambient temperature under argon for 3 hrs. Dibromomaleimide (36 mg, 0.9 eq), in MeOH (5 ml) was then added to the reaction mixture. After 30 mins NaOAc (56 mg, 4 eq), was added to the reaction mixture and the solvent evaporated in vacuo. The residue was worked up with DCM and brine. The organic layers were combined, dried (MgSO4), filtered and concentrated in vacuo. Purification by flash chromatography (silica gel, 0-20% EtOAc-DCM) afforded the desired compound as a yellow gum (40 mg, 40%). 1HNMR (CDCl3, 600 MHz), delta8.5 (2H, d J 8.5 Hz aromatic H’s), delta8.2 (4H, m aromatic H’s), delta7.53 (1H, s CONH), delta7.46 (4H, m, aromatic H’s), delta7.1 (2H, d, J=7.4 Hz aromatic H’s), delta5.65 (2H, t, J 6.27 SO2NH), delta3.3 (4H, t, J 6.0 SCH2), delta3.17 (4H, q, J 6.0 NHCH2), delta2.8 (12H, s NCH3); 13CNMR (CDCl3, 150 MHz), 6165.9, 152.0, 136.5, 134.7, 130.7, 129.94, 129.85, 129.62, 129.57, 128.63, 123.3, 118.8, 115.4, 45.5, 43.6, 31.8; IR (cm-1) 3288 (br) 1720 (s) MS (Na+) m/z relative intensity: 736 (M, 100); Exact mass calculated for [C32H35N5O6NaS4] requires m/z 736.1368. Found 736.1390 (Na+)., 1122-10-7

There are, however, a few established termolecular elementary reactions. The reaction of nitric oxide with oxygen appears to involve termolecular steps. you can also browse my other articles about 1122-10-7

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Patent; UCL Business Plc; Smith, Mark; Caddick, Stephen; Baker, James; Chudasama, Vijay; (80 pag.)US9295729; (2016); B2;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem

1122-10-7, A balanced equation for a chemical reaction indicates what is reacting and what is produced, but it reveals nothing about how the reaction actually takes place. The reaction mechanism is the process, or pathway, by which a reaction occurs.1122-10-7, name is 3,4-Dibromo-1H-pyrrole-2,5-dione. An updated downstream synthesis route of 1122-10-7 as follows.

General procedure: To a stirred solution of 2,3-dibromomaleimide23 (1.0 mmol) in CH2Cl2 (20ml) Et3N (2.0mmol) and thiol (2.1mmol) were added under argon atmosphere and stirred for 3 h at room temperature. The reaction mixture was evaporated,and the crude product was purified by flash chromatography to give the desired compound.

A chemical reaction often occurs in steps, although it may not always be obvious to an observer. Thank you very much for taking the time to read this article. If you are also interested in other aspects of 3,4-Dibromo-1H-pyrrole-2,5-dione, you can also browse my other articles.

Reference£º
Article; Csavas, Magdolna; Miskovics, Adrienn; Szcs, Zsolt; Rth, Erzsebet; Nagy, Zsolt L; Bereczki, Ilona; Herczeg, Mihaly; Batta, Gyula; Nemes-Nikodem, Eva; Ostorhazi, Eszter; Rozgonyi, Ferenc; Borbas, Aniko; Herczegh, Pal; Journal of Antibiotics; vol. 68; 9; (2015); p. 579 – 585;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem

The molecularity of an elementary reaction is the number of molecules that collide during that step in the mechanism. If there is only a single reactant molecule in an elementary reaction, that step is designated as unimolecular.1122-10-7, name is 3,4-Dibromo-1H-pyrrole-2,5-dione. A new synthetic method of this compound is introduced below., 1122-10-7

General procedure: To a stirred solution of 2,3-dibromomaleimide23 (1.0 mmol) in CH2Cl2 (20ml) Et3N (2.0mmol) and thiol (2.1mmol) were added under argon atmosphere and stirred for 3 h at room temperature. The reaction mixture was evaporated,and the crude product was purified by flash chromatography to give the desired compound.

Thank you very much for taking the time to read this article. If you are also interested in other aspects of 1122-10-7, you can also browse my other articles.

Reference£º
Article; Csavas, Magdolna; Miskovics, Adrienn; Szcs, Zsolt; Rth, Erzsebet; Nagy, Zsolt L; Bereczki, Ilona; Herczeg, Mihaly; Batta, Gyula; Nemes-Nikodem, Eva; Ostorhazi, Eszter; Rozgonyi, Ferenc; Borbas, Aniko; Herczegh, Pal; Journal of Antibiotics; vol. 68; 9; (2015); p. 579 – 585;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem

1122-10-7, A balanced equation for a chemical reaction indicates what is reacting and what is produced, but it reveals nothing about how the reaction actually takes place. The reaction mechanism is the process, or pathway, by which a reaction occurs.1122-10-7, name is 3,4-Dibromo-1H-pyrrole-2,5-dione. An updated downstream synthesis route of 1122-10-7 as follows.

To a stirred solution of 2,3-dibromomaleimide (255 mg, 1.0 mmol) in CH2Cl2 (20 mL) Et3N(2.0 mmol, 278 mL) and 1-mercapto-11-hydroxy-3,6,9-trioxaundecane (402 ml, 2.1 mmol) were added under an argon atmosphereand stirred for 3 h at room temperature. The reactionmixturewas evaporated, and the crude product was converted intoN-ethoxycarbonyl compound and worked up according to generalmethod A yielding compound 32b which was used in further stepswithout purification

This molecular description is the mechanism of the reaction; it describes how individual atoms, ions, or molecules interact to form particular products.If you are interested, you can also browse other articles of 3,4-Dibromo-1H-pyrrole-2,5-dione. We look forward to the emergence of more reaction modes in the future.

Reference£º
Article; Sz?cs, Zsolt; Kelemen, Viktor; Le Thai, Son; Csavas, Magdolna; R?th, Erzsebet; Batta, Gyula; Stevaert, Annelies; Vanderlinden, Evelien; Naesens, Lieve; Herczegh, Pal; Borbas, Aniko; European Journal of Medicinal Chemistry; vol. 157; (2018); p. 1017 – 1030;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem