Tag: M.W:0-100

872-32-2, A balanced equation for a chemical reaction indicates what is reacting and what is produced, but it reveals nothing about how the reaction actually takes place. The reaction mechanism is the process, or pathway, by which a reaction occurs.872-32-2, name is 2-Methyl-1-pyrroline. An updated downstream synthesis route of 872-32-2 as follows.

General procedure: 2-Methyl-pyrroline (1equiv.) was added to a suspension of an enzyme (20% weight) in a mixture of toluene/water (20mL/100muL), followed by the addition of benzylamine (1equiv.) and isocyanoester 1 (1equiv.). The mixture was stirred at room temperature. The enzyme and water were filtered off through a funnel containing Celite and MgSO4. The solvent was then evaporated in vacuum. The product was purified by column chromatography (silica gel, DCM/methanol).

A chemical reaction often occurs in steps, although it may not always be obvious to an observer. Thank you very much for taking the time to read this article. If you are also interested in other aspects of 2-Methyl-1-pyrroline, you can also browse my other articles.

Reference£º
Article; Wilk, Monika; Brodzka, Anna; Koszelewski, Dominik; Madej, Arleta; Paprocki, Daniel; ??d?o-Dobrowolska, Anna; Ostaszewski, Ryszard; Bioorganic Chemistry; vol. 93; (2019);,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem

541-59-3, A balanced equation for a chemical reaction indicates what is reacting and what is produced, but it reveals nothing about how the reaction actually takes place. The reaction mechanism is the process, or pathway, by which a reaction occurs.541-59-3, name is Maleimide. An updated downstream synthesis route of 541-59-3 as follows.

To a solution of maleimide (6.35 g, 65.4 mmol, 1.0 eq. ) in EtOAc (120 mL) were added N-methyl morpholine (8.6 mL, 78.5 mmol, 1.2 eq. ) and methyl chloroformate (6.0 mL, 78.5 mmol, 1.2 eq. ) at 0 . The reaction was stirred at 0 for 30 min and r.t. 1 h. The solid was filtered off and filtrate concentrated. The residue was dissolved in CH2Cl2and filtered through a silica gel plug and eluated with CH2Cl2to remove the color. The appropriate fractions were concentrated and resulted solid was triturated with 10%EtOAc/PE to give a white solid (9.00 g, 89%yield) .

A chemical reaction often occurs in steps, although it may not always be obvious to an observer. Thank you very much for taking the time to read this article. If you are also interested in other aspects of Maleimide, you can also browse my other articles.

Reference£º
Patent; HANGZHOU DAC BIOTECH CO. LTD; ZHAO, Robert Yongxin; YANG, Qingliang; HUANG, Yuanyuan; ZHAO, Linyao; GAI, Shun; YE, Hangbo; LEI, Jun; XU, Yifang; CAO, Mingjun; GUO, Huihui; JIA, Junxiang; TONG, Qianqian; LI, Wenjun; ZHOU, Xiaomai; XIE, Hongsheng; BAI, Lu; CAI, Xiang; ZHUO, Xiaotao; ZHANG, Xiuzheng; ZHENG, Jun; (424 pag.)WO2019/127607; (2019); A1;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem

5264-35-7, 5-Methoxy-3,4-dihydro-2H-pyrrole is a pyrrolines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Reference Example 144; 5-Methoxy-3,4-dihydro-2H-pyrrole and triethylamine were added to ethyl 3-oxo-3-(2, 4,5-trifluorophenyl)propanoate, for stirring at 60¡ãC for 4 days, to obtain ethyl 3-oxo-2-pyrrolidin-2-ylidene-3-(2,4,5-trifluorophenyl)propanoate., 5264-35-7

The synthetic route of 5264-35-7 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Astellas Pharma Inc.; EP1650192; (2006); A1;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem

5264-35-7,5264-35-7, 5-Methoxy-3,4-dihydro-2H-pyrrole is a pyrrolines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

2-pyrrolidinone was combined with dimethylsulphate in benzene and refluxed for 3 h. After purification including distillation, the resulting 2-methylimino ester pyrrolidine was combined with excess lithium phenoxide (PhLi) in dry ether at room temperature for 18 h to yield the title compound.

The synthetic route of 5264-35-7 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Benkovic, Stephen J.; Shapiro, Lucy; Wright, Rachel; Stephens, Craig; Kahng, Lyn Sue; Berdis, Anthony; Lee, Irene; US2005/227933; (2005); A1;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem

5264-35-7, 5-Methoxy-3,4-dihydro-2H-pyrrole is a pyrrolines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,5264-35-7

The reaction mixture comprising 1 mmol of 1-[N-(5,5-dimethyl-3,4,5,6-tetrahydropyrimidinium-2-yl)amino]dodecane-12-ammonium ditrifluoroacetate, 1 mmol (1 eq.) of 3,4-dihydro-5-methoxy-2H-pyrrole and 0.5 ml of triethylamine in 10 ml of absolute ethanol is heated under reflux for 20 hours. After cooling down to ambient temperature, the reaction mixture is evaporated to dryness and chromatographed on a silica column (CH2Cl2/CH3OH/NH4OH 85:13:2) in order to produce the product, in the form of an oil, with a yield of 65percent. NMR 1H (CD3OD, 360 MHz), delta (ppm): 1.12 (s, 6H); 1.36 (m, 16H); 1.60 (n, 2H); 1.69 (m, 2H); 2.28 (m, 2H); 2.93 (m, 2H); 3.09 (s, 4H); 3.22 (m, 2H); 3.31 (m, 2H); 3.75 (m, 2H). MS-ES+: [M+H]+: 378; [M+H+TFA]+: 492; [M+2H]++/2: 189.5

As the paragraph descriping shows that 5264-35-7 is playing an increasingly important role.

Reference£º
Patent; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.; US2005/176819; (2005); A1;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.5264-35-7,5-Methoxy-3,4-dihydro-2H-pyrrole,as a common compound, the synthetic route is as follows.

3. 2-diphenylpyrrole (Compound 76) 2-pyrrolidinone was combined with dimethylsulphate in benzene and refluxed for 3h. After purification including distillation, the resulting 2-methylimino ester pyrrolidine was combined with excess lithium phenoxide (PhLi) in dry ether at room temperature for 18h to yield the title compound., 5264-35-7

As the paragraph descriping shows that 5264-35-7 is playing an increasingly important role.

Reference£º
Patent; The Penn State Research Foundation; EP1420021; (2004); A1;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.5264-35-7,5-Methoxy-3,4-dihydro-2H-pyrrole,as a common compound, the synthetic route is as follows.

A mixture of chelate 8 (0.32 g, 1 mmol) and butyrolactim 2a (n = 1) (0.39 g, 4 mmol) was refluxed in toluene (7 mL) for 20 h. The solvent was evaporated, the residue was three times crystallized from ethanol to obtain chelate 10a (0.16 g, 42percent) with m.p. 235?236 C (decomp.)., 5264-35-7

5264-35-7 5-Methoxy-3,4-dihydro-2H-pyrrole 353443, apyrrolines compound, is more and more widely used in various fields.

Reference£º
Article; Ruban; Potapova; Baranin; Dorokhov; Russian Chemical Bulletin; vol. 63; 10; (2014); p. 2260 – 2263; Izv. Akad. Nauk, Ser. Khim.; vol. 63; 10; (2014); p. 2260 – 2263,4;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem

872-32-2, 2-Methyl-1-pyrroline is a pyrrolines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

872-32-2, Intermediate (i) 2-Methyl-[1 ,3′]bipyrrolidinyl-1 ‘-carboxylic acid tert-butyl esterTo a solution of N-BOC-3-pyrrolidinone (4.22g, 22.9 mmol) and 2- methylpyrroline (1.95 g, 22.9 mmol) (HCI salt was made by addition of 22.9 mL of 1 M HCI in ether into the DCM solution of 2-methylpyrroline, then evaporated) in DCE (60 ml_) was added powdered sodium triacetoxyborohydride slowly under N2 at r.t. The yellowish milky solution was stirred at r.t. overnight. LC/MS – m/z 255 and 199 (base and M-tBu).The reaction was quenched with aq. NaHCO3 solution (100 ml_). The two layers were separated, and the aqueous layer was extracted with DCM (20 ml_ x 2). The combined DCM extracts were washed with sodium bicarbonate (10 ml_), and brine (5 ml_x2), dried (anhydrous potassium carbonate), filtered, and concentrated in vacuo. The crude product was purified on a silica gel column, eluted with DCM and 7.5percent MeOH in DCM to get 5.50 g (yield: 94percent) of the title compound as a liquid. MS: 255 (M+H+); TLC: 0.5 (10percent MeOH in DCM).

As the paragraph descriping shows that 872-32-2 is playing an increasingly important role.

Reference£º
Patent; SANOFI-AVENTIS; GAO, Zhongli; HARTUNG, Ryan; STEFANY, David; WO2010/65798; (2010); A1;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem

872-32-2, 2-Methyl-1-pyrroline is a pyrrolines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,872-32-2

General procedure: A mixture of 2-methyl-1-pyrroline (2.8 g, 33.7 mmol) and the corresponding cyclic phosphite 2a-2e (30.6 mmol) were stirred in toluene (5 mL) for 4-6 h at room temperature (conversion was checked by TLC or 31P NMR), the mixture was poured into 30 mL water, slowly acidified to pH 3 with 11 N HCl then quickly extracted with tert-butyl methyl ether (TBME) (3 .x. 20 mL). The aqueous phase was basified to pH 9-10 with NaOH pellets then extracted with CH2Cl2 (4 .x. 20 mL). The combined organic phases were dried over MgSO4, filtered and roto-evaporated to give the crude aminophosphonates 3a-3e as white powders which were then purified by SiO2 column chromatography with eluent CH2Cl2/EtOH 8/1.

As the paragraph descriping shows that 872-32-2 is playing an increasingly important role.

Reference£º
Article; Gosset, Gae?lle; Cle?ment, Jean-Louis; Culcasi, Marcel; Rockenbauer, Antal; Pietri, Sylvia; Bioorganic and Medicinal Chemistry; vol. 19; 7; (2011); p. 2218 – 2230;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem